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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYS1
All Species:
37.58
Human Site:
S59
Identified Species:
75.15
UniProt:
Q8N2H4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N2H4
NP_291020.1
156
17615
S59
D
A
E
I
L
G
F
S
T
P
P
G
R
L
S
Chimpanzee
Pan troglodytes
XP_514675
276
30313
S179
D
A
E
I
L
G
F
S
T
P
P
G
R
L
S
Rhesus Macaque
Macaca mulatta
XP_001109290
252
27995
S155
D
A
E
I
L
G
F
S
T
P
P
G
R
L
S
Dog
Lupus familis
XP_543018
152
17075
S59
D
A
E
I
L
G
F
S
T
P
P
G
R
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q78S06
156
17535
S59
D
A
E
I
L
G
F
S
T
P
P
G
R
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508808
264
29018
S167
N
Y
E
I
L
G
F
S
T
P
P
G
R
L
S
Chicken
Gallus gallus
XP_417361
156
17398
S59
S
D
E
I
L
G
F
S
T
P
P
G
R
L
S
Frog
Xenopus laevis
NP_001079422
156
17940
S59
N
Y
E
V
L
G
F
S
S
V
P
G
R
V
S
Zebra Danio
Brachydanio rerio
XP_001918846
156
17784
S59
S
Y
E
V
L
G
F
S
T
T
H
G
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649809
160
18270
Y60
E
Y
H
E
I
H
I
Y
D
M
G
G
R
L
V
Honey Bee
Apis mellifera
XP_001120649
160
18473
R62
H
Y
K
E
I
H
V
R
D
F
A
G
Q
F
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796556
155
17604
S59
G
Y
D
C
L
D
F
S
S
S
G
G
R
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.7
61.9
80.1
N.A.
97.4
N.A.
N.A.
54.1
79.4
75
73.7
N.A.
43.7
43.1
N.A.
51.9
Protein Similarity:
100
56.5
61.9
83.9
N.A.
98.7
N.A.
N.A.
56.8
86.5
87.1
87.1
N.A.
63.7
65.6
N.A.
69.8
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
86.6
60
66.6
N.A.
20
6.6
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
86.6
86.6
73.3
N.A.
33.3
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
0
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
9
9
0
0
9
0
0
17
0
0
0
0
0
0
% D
% Glu:
9
0
75
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
84
0
0
9
0
0
0
9
0
% F
% Gly:
9
0
0
0
0
75
0
0
0
0
17
100
0
0
0
% G
% His:
9
0
9
0
0
17
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
59
17
0
9
0
0
0
0
0
0
0
17
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
84
0
0
0
0
0
0
0
0
75
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% M
% Asn:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
59
67
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
92
0
0
% R
% Ser:
17
0
0
0
0
0
0
84
17
9
0
0
0
0
75
% S
% Thr:
0
0
0
0
0
0
0
0
67
9
0
0
0
0
0
% T
% Val:
0
0
0
17
0
0
9
0
0
9
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _